Immunoglobulin heavy chain switch region gene polymorphisms in glomerulonephritis
نویسندگان
چکیده
منابع مشابه
Relation of mesangial IgA glomerulonephritis to polymorphism of immunoglobulin heavy chain switch region.
We have investigated the switch regions of Ig heavy chain genes of patients with IgA glomerulonephritis (IgA-GN) using restriction fragment length polymorphism (RFLP) analysis. Genomic DNA from patients and controls was digested with the restriction endonuclease Sst I and transferred to nylon membranes using the Southern blot procedure and hybridized with a probe homologous to the switch region...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1990
ISSN: 0085-2538
DOI: 10.1038/ki.1990.205